Our History

Dr. Ehrenfeld, Dr. Wylie, and Dr. Stoney

William K. Ehrenfeld (left) and Ronald J. Stoney (right) with their mentor Edwin Jack Wylie (circa 1973)

Vascular Cures was established in 1982 as the Pacific Vascular Research Foundation (PVRF) by Ronald J. Stoney, MD and William K. Ehrenfeld, MD, vascular surgeons at the University of California, San Francisco. PVRF initially supported vascular surgeons who conducted research to develop innovative treatment strategies for vascular diseases.

In 1990, the foundation also began supporting basic vascular science, focusing on the causes and mechanisms of vascular disease. In the second part of the decade, Vascular Cures established the Wylie Scholar Program, designed to develop vascular surgeons into first-rate research scientists who would pursue discovery of new treatments while continuing to work directly with patients.

In 2000, Vascular Cures founded the Laboratory for Accelerated Vascular Research (LAVR) at UCSF, a unique collaboration of scientists and physicians who work side-by-side to generate new knowledge in vascular biology and device technology that improves the treatment of vascular diseases. LAVR was funded by Vascular Cures and the Wayne & Gladys Valley Foundation through 2010.

In 2013, Vascular Cures launched its latest initiative, the Vascular Cures Research Network, a collaborative research consortium of world class investigators focused on solving the most urgent problems of patients with vascular disease. This collaborative network of researchers share research results and jointly create Vascular Cures' National Vascular Biobank, to accelerate precision medicine and, ultimately, save lives.

In 2014, Vascular Cures organized the first Vascular Innovation Summit bringing together leaders from healthcare systems, academic medical centers, industry, payers, investors and regulators to develop and pursue collaborative projects. The first of these projects is Project VOICE who's goal is to improve outcomes in peripheral artery disease (PAD) through patient empowerment, patient-reported outcomes research and collaborations that transform the way healthcare is delivered. Learn more about this new initiative here.

In 2014, Vascular Cures acquired most of the Vascular Disease Foundation's (VDF) digital assets and educational resources. VDF ceased operations in January 2014. VDF was founded in 1998 with the mission to provide public education and improving awareness about vascular diseases. Vascular Cures is now the only organization in the country dedicated exclusively to finding cures for vascular disease and to provide resources, information, and education to patients with vascular diseases outside the heart.

In 2016, Vascular Cures launched the pilot study for Project VOICE at Wake Forest University to help patients with Peripheral Artery Disease become more engaged in their care while improving patient-reported outcomes.

In September 2016, Vascular Cures held the inaugural Research Summit to identify high priority areas of unmet scientific needs, suitable for innovative pilot projects that could have a rapid impact on vascular medicine/surgery.


Vascular Cures is at the forefront of vascular research. Our advances include gene therapy to develop new blood vessels, medical devices to avoid major surgery, and human tissue-based grafts to improve outcomes. To learn more about Vascular Cures' programs click here.